IGF-1LR3

0.1mg x 10 vials

$310.00 AUD

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Product Overview

IGF-1 LR3 (Long Arginine 3 Insulin-like Growth Factor-1) is a synthetic, recombinant analogue of the mammalian IGF-1 peptide. It has been engineered with a 13-amino acid N-terminal extension and a substitution of Arginine for Glutamic acid at the third position. These structural modifications result in a compound that is significantly more potent than native IGF-1, with a markedly extended half-life of approximately 20–30 hours.

In laboratory research, IGF-1 LR3 is utilized to study cellular growth and metabolic pathways, focusing on:

Receptor Affinity: Designed with a significantly reduced affinity for IGF-binding proteins (IGFBPs), allowing more of the active peptide to interact with the IGF-1 receptor.
Hyperplasia Research: Studied for its potential to stimulate mitogenesis and the proliferation of new muscle cells (hyperplasia) rather than just increasing the size of existing cells.
Nutrient Partitioning: Investigated for its ability to enhance glucose uptake and amino acid transport, facilitating research into fat metabolism and energy expenditure.
Cellular Repair: Researched for its role in activating the PI3K-Akt signaling pathway, which is essential for tissue regeneration and protein synthesis.

Laboratory Research Warning

This product is strictly for laboratory research purposes only. This compound is not for human use, veterinary use, or therapeutic consumption. It has not been evaluated by the FDA. By purchasing, the buyer acknowledges that this is a research chemical intended for use by qualified professionals in a controlled environment.